SCHEMBL873779

SCHEMBL873779

CN(C)c1cccc2c1C(=O)NC2=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.55
▸ MAPT P10636 3/20 0.55
▸ TDP1 Q9NUW8 3/20 0.55
▸ L3MBTL1 Q9Y468 2/20 0.55
▸ NSD2 O96028 1/20 0.55
▸ EGFR P00533 1/20 0.55
▸ LMNA P02545 1/20 0.55
▸ MAPK1 P28482 1/20 0.55
▸ KDM4E B2RXH2 3/20 0.47
▸ GAA P10253 2/20 0.47
▸ HPGD P15428 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ GSK3B P49841 3/20 0.46
▸ PARP1 P09874 5/20 0.44
▸ CASP3 P42574 3/20 0.41
▸ PDK2 Q15119 1/20 0.41
▸ CASP7 P55210 2/20 0.41
▸ CASP2 P42575 1/20 0.41
▸ CASP6 P55212 1/20 0.41
▸ CASP8 Q14790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27387856 0.81 EGFR (0.52) ALDH1A1MAPTTDP1L3MBTL1NSD2
SCHEMBL16754925 0.77 GSK3B (0.62) ALDH1A1MAPTTDP1L3MBTL1KDM4E
SCHEMBL18984785 0.75 MAPT (0.88) ALDH1A1MAPTTDP1L3MBTL1NSD2
SCHEMBL4887196 0.75 KDM4E (0.40) ALDH1A1MAPTTDP1L3MBTL1NSD2
SCHEMBL29485716 0.74 GSK3B (0.52) ALDH1A1MAPTTDP1KDM4EGAA
SCHEMBL112742 0.74 GSK3B (0.52) ALDH1A1MAPTTDP1KDM4EGAA
SCHEMBL28210009 0.74 GSK3B (0.52) ALDH1A1MAPTTDP1L3MBTL1KDM4E
SCHEMBL18984695 0.74 MAPT (0.85) ALDH1A1MAPTTDP1L3MBTL1NSD2
SCHEMBL3501337 0.73 MEN1 (0.69) ALDH1A1MAPTTDP1L3MBTL1NSD2
SCHEMBL30831694 0.73 MEN1 (0.69) ALDH1A1MAPTTDP1L3MBTL1NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024049924-A1 OPTICAL SYSTEMS AND PLATFORMS FOR SIMULTANEOUSLY ANALYZING MULTIPLE SOLUTION PROPERTIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-07 — — WO claimed
WO-2024049924-A1 OPTICAL SYSTEMS AND PLATFORMS FOR SIMULTANEOUSLY ANALYZING MULTIPLE SOLUTION PROPERTIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-07 — — WO disclosed
US-9889213-B2 Multimodal imaging of fibrin THE GENERAL HOSPITAL CORPORATION (US) 2018-02-13 — — US disclosed
US-20160199519-A1 Multimodal Imaging of Fibrin THE GENERAL HOSPITAL CORPORATION 2016-07-14 — — US disclosed
US-9200017-B2 Multimodal imaging of fibrin THE GENERAL HOSPITAL CORPORATION (US) 2015-12-01 — — US disclosed
US-8440835-B2 Environmentally sensitive fluorophores MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-05-14 — — US disclosed
US-20120077958-A1 Multimodal Imaging of Fibrin THE GENERAL HOSPITAL CORPORATION 2012-03-29 — — US disclosed
WO-2010121133-A2 MULTIMODAL IMAGING OF FIBRIN THE GENERAL HOSPITAL CORPORATION (US) 2010-10-21 — — WO disclosed
US-20100168428-A1 ENVIRONMENTALLY SENSITIVE FLUOROPHORES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-07-01 — — US disclosed
WO-2009056782-A1 LUMINESCENCE UCL BUSINESS PLC (GB) 2009-05-07 — — WO disclosed
WO-2008106104-A2 ENVIRONMENTALLY SENSITIVE FLUOROPHORES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-09-04 — — WO disclosed
US-6468730-B2 DI- OR TRIHALO-SUBSTITUTED CARBOXY OR SULFONIC ACID STORAGE STABILIZER FUJI PHOTO FILM CO., LTD. (JP) 2002-10-22 — — US disclosed
US-20020015926-A1 IMAGE RECORDING MATERIAL FUJIFILM CORPORATION (JP) 2002-02-07 — — US disclosed
US-4144072-A CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE FUJI PHOTO FILM CO., LTD. (JP) 1979-03-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100168428-A1 ENVIRONMENTALLY SENSITIVE FLUOROPHORES PTMS, IK, PHAX ALDH1A1 4233/4885MAPT 1367/4885TDP1 1447/4885
US-20120077958-A1 Multimodal Imaging of Fibrin FGB, F2, SERPINC1 ALDH1A1 4653/4885MAPT 2472/4885TDP1 874/4885
US-20160199519-A1 Multimodal Imaging of Fibrin FGB, F2, SERPINC1 ALDH1A1 4653/4885MAPT 2472/4885TDP1 874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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