Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 1.00 |
| ▸ | DRD2 | P14416 | 10/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.75 |
| ▸ | DRD4 | P21917 | 7/20 | 0.67 |
| ▸ | DRD1 | P21728 | 5/20 | 0.67 |
| ▸ | DRD5 | P21918 | 5/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | PRCP | P42785 | 1/20 | 0.65 |
| ▸ | EBP | Q15125 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873078 | 1.00 | DRD3 (1.00) | DRD3DRD2SIGMAR1DRD4DRD1 | |
| SCHEMBL873549 | 1.00 | DRD3 (1.00) | DRD3DRD2SIGMAR1DRD4DRD1 | |
| SCHEMBL29369425 | 1.00 | DRD3 (1.00) | DRD3DRD2SIGMAR1DRD4DRD1 | |
| Hydrochloric Acid SCHEMBL5678691 | 0.99 | DRD3 (0.98) | DRD3DRD2SIGMAR1DRD4DRD1 | |
| Hydrochloric Acid SCHEMBL5678697 | 0.99 | DRD3 (0.98) | DRD3DRD2SIGMAR1DRD4DRD1 | |
| Bromide SCHEMBL7023734 | 0.99 | DRD3 (0.98) | DRD3DRD2SIGMAR1DRD4DRD1 | |
| Bromide SCHEMBL5699015 | 0.99 | DRD3 (0.98) | DRD3DRD2SIGMAR1DRD4DRD1 | |
| Hydrochloric Acid SCHEMBL29634866 | 0.99 | DRD3 (0.98) | DRD3DRD2SIGMAR1DRD4DRD1 | |
| SCHEMBL6880380 | 0.92 | DRD3 (0.84) | DRD3DRD2SIGMAR1DRD4DRD1 | |
| SCHEMBL6881711 | 0.92 | DRD3 (0.84) | DRD3DRD2SIGMAR1DRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2618826-B1 | PHENYLPIPERIDINE COMPOUNDS FOR THE TREATMENT OF DEMENTIA | CARLSSON A RESEARCH AB (SE) | 2016-04-13 | — | — | EP | claimed |
| US-20130197032-A1 | PHENYLPIPERIDINE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | A. CARLSSON RESEARCH AB (SE) | 2013-08-01 | — | — | US | claimed |
| EP-2618826-A1 | PHENYLPIPERIDINE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | A.Carlsson Research AB (SE) | 2013-07-31 | — | — | EP | claimed |
| WO-2012039660-A1 | PHENYLPIPERIDINE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | A. CARLSSON RESEARCH AB (SE) | 2012-03-29 | — | — | WO | claimed |
| EP-2618826-B1 | PHENYLPIPERIDINE COMPOUNDS FOR THE TREATMENT OF DEMENTIA | CARLSSON A RESEARCH AB (SE) | 2016-04-13 | — | — | EP | disclosed |
| US-20130197032-A1 | PHENYLPIPERIDINE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | A. CARLSSON RESEARCH AB (SE) | 2013-08-01 | — | — | US | disclosed |
| EP-2618826-A1 | PHENYLPIPERIDINE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | A.Carlsson Research AB (SE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012039660-A1 | PHENYLPIPERIDINE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | A. CARLSSON RESEARCH AB (SE) | 2012-03-29 | — | — | WO | disclosed |
| US-6962998-B2 | Processes for producing racemic piperidine derivative and for producing optically active piperidine derivative | TORAY INDUSTRIES, INC. (JP) | 2005-11-08 | — | — | US | disclosed |
| US-20030130313-A1 | Processes for producing racemic piperidine derivative and for producing optically active piperidine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1295873-A1 | PROCESSES FOR PRODUCING RACEMIC PIPERIDINE DERIVATIVE AND FOR PRODUCING OPTICALLY ACTIVE PIPERIDINE DERIVATIVE | TORAY INDUSTRIES, INC. (JP) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130313-A1 | Processes for producing racemic piperidine derivative and for producing optically active piperidine derivative | AMPD2, AMPD1, ITPA | DRD3 40/4885DRD2 16/4885SIGMAR1 756/4885 |
| US-20130197032-A1 | PHENYLPIPERIDINE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | HTR5A, HTR2A, HTR1A | DRD3 186/4885DRD2 36/4885SIGMAR1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.