Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845935 | 0.85 | PABPC1 (0.44) | GAAKDM4ELMNAPABPC1MAPK1 | |
| SCHEMBL845131 | 0.85 | PABPC1 (0.49) | GAAKDM4ELMNAPABPC1MAPK1 | |
| SCHEMBL845007 | 0.85 | PABPC1 (0.49) | GAAKDM4ELMNAPABPC1MAPK1 | |
| SCHEMBL10119511 | 0.81 | GAA (0.44) | GAAKDM4ELMNAPABPC1MAPK1 | |
| SCHEMBL845431 | 0.81 | TRPV1 (0.43) | GAAKDM4ELMNAPABPC1MAPK1 | |
| SCHEMBL13272394 | 0.81 | MEN1 (0.47) | GAAKDM4ELMNAPABPC1MAPK1 | |
| SCHEMBL10119504 | 0.81 | GAA (0.42) | GAAKDM4ELMNAPABPC1MAPK1 | |
| SCHEMBL845337 | 0.79 | GAA (0.45) | GAAKDM4ELMNAPABPC1MAPK1 | |
| SCHEMBL871645 | 0.79 | PABPC1 (0.43) | GAAKDM4ELMNAPABPC1MAPK1 | |
| SCHEMBL845301 | 0.78 | PABPC1 (0.51) | GAAKDM4ELMNAPABPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |