Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845021 | 0.89 | ALDH1A1 (0.53) | PABPC1ALDH1A1MAPK1HTTCYP2C9 | |
| SCHEMBL10119511 | 0.88 | GAA (0.44) | PABPC1ALDH1A1MAPK1HTTCYP2C9 | |
| SCHEMBL873862 | 0.81 | ALDH1A1 (0.45) | PABPC1ALDH1A1MAPK1HTTCYP2C9 | |
| SCHEMBL845567 | 0.81 | ALDH1A1 (0.50) | PABPC1ALDH1A1MAPK1HTTCYP2C9 | |
| SCHEMBL10119504 | 0.81 | GAA (0.42) | PABPC1ALDH1A1MAPK1HTTCYP2C9 | |
| SCHEMBL845005 | 0.80 | KDM4E (0.54) | PABPC1ALDH1A1CYP2C9CYP2C19KDM4E | |
| SCHEMBL845284 | 0.79 | MAPK1 (0.58) | PABPC1ALDH1A1MAPK1HTTCYP2C9 | |
| SCHEMBL873858 | 0.79 | GAA (0.42) | PABPC1ALDH1A1MAPK1HTTCYP2C9 | |
| SCHEMBL845518 | 0.79 | GAA (0.52) | PABPC1ALDH1A1MAPK1HTTCYP2C9 | |
| SCHEMBL845312 | 0.78 | GAA (0.60) | PABPC1ALDH1A1MAPK1HTTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |