SCHEMBL873949

SCHEMBL873949

I[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
ALDH1A1 P00352 5/20 0.35
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
MIF P14174 1/20 0.32
HPGD P15428 3/20 0.32
HSD17B10 Q99714 3/20 0.32
ALOX12 P18054 2/20 0.32
NOTUM Q6P988 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
TSHR P16473 4/20 0.32
TDP1 Q9NUW8 3/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL874968 0.79 ESR1 (0.36) RAB9AMEN1KMT2AESR1ESR2
SCHEMBL874349 0.79 ESR1 (0.36) RAB9AMEN1KMT2AESR1ESR2
SCHEMBL12447024 0.78 CYP1A1 (0.39) ALDH1A1HPGDHSD17B10ALOX12TDP1
SCHEMBL18108128 0.73 ALDH1A1 (0.35) RAB9AESR1ESR2ALDH1A1NPC1
SCHEMBL18108392 0.73 TSHR (0.35) RAB9AESR1ESR2ALDH1A1NPC1
SCHEMBL7665890 0.73 ESR1 (0.44) RAB9AESR1ESR2ALDH1A1NPC1
SCHEMBL8967403 0.73 ESR1 (0.44) RAB9AESR1ESR2ALDH1A1NPC1
SCHEMBL18108083 0.73 ALDH1A1 (0.35) RAB9AESR1ESR2ALDH1A1NPC1
SCHEMBL18108178 0.73 ALDH1A1 (0.35) RAB9AESR1ESR2ALDH1A1NPC1
SCHEMBL18108202 0.73 ESR1 (0.44) RAB9AESR1ESR2ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2024-07-18 US claimed
CN-114716345-A Method for deoxygenation functionalization and deoxygenation activation of alcohols and alcohol-functionalized materials 山东博苑医药化学股份有限公司 2022-07-08 CN claimed
EP-1939221-B1 A METHOD FOR PRODUCING FUNCTIONALIZED CIS-1,4POLYDIENES HAVING HIGH CIS-1,4-LINKAGE CONTENT AND HIGH FUNCTIONALITY BRIDGESTONE CORP (JP) 2017-10-18 EP claimed
CN-102746542-B A method for producing functionalized cis-1,4polydienes having high cis-1,4-linkage content and high functionality BRIDGESTONE CORP 2015-05-20 CN claimed
US-8017695-B2 homo or copolymerizing 1,3-butadiene in prseence of a catalyst system containing lanthanium neodecanoate, methylaluminoxane, diisobutylaluminum hydride, diethylaluminum choride, followed by reacting reactive polymer with bis/diethylamino/benzophenone; narrow molecular weight distribution BRIDGESTONE CORPORATION (JP) 2011-09-13 US claimed
US-7825201-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2010-11-02 US claimed
EP-1435362-B1 Process for polymer hydrogenation using lithium hydride prepared from reactor equipped with high-speed injection nozzle KOREA KUMHO PETROCHEM CO LTD (KR) 2010-03-03 EP claimed
US-20090299019-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2009-12-03 US claimed
US-20080182954-A1 METHOD FOR PRODUCING FUNCTIONALIZED CIS-1,4-POLYDIENES HAVING HIGH CIS-1,4-LINKAGE CONTENT AND HIGH FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2008-07-31 US claimed
EP-1939221-A2 A method for producing functionalized cis-1,4polydienes having high cis-1,4-linkage content and high functionality Bridgestone Corporation (JP) 2008-07-02 EP claimed
US-6864326-B2 Process for polymer hydrogenation using lithium hydride prepared from reactor equipped with high-speed injection nozzle KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2005-03-08 US claimed
EP-1124863-B1 PROCESS FOR HYDROGENATING A CONJUGATED DIENE POLYMER KOREA KUMHO PETROCHEM CO LTD (KR) 2004-07-21 EP claimed
US-20040132916-A1 Process for polymer hydrogenation using lithium hydride prepared from reactor equipped with high-speed injection nozzle KOREA KUMHO PETROCHEMICAL CO., LTD. 2004-07-08 US claimed
EP-1435362-A1 Process for polymer hydrogenation using lithium hydride prepared from reactor equipped with high-speed injection nozzle Korea Kumho Petrochemical Co. Ltd. (KR) 2004-07-07 EP claimed
EP-1124863-A1 PROCESS FOR HYDROGENATING A CONJUGATED DIENE POLYMER Korea Kumho Petrochemical Co. Ltd. (KR) 2001-08-22 EP claimed
WO-2000008069-A1 PROCESS FOR HYDROGENATING A CONJUGATED DIENE POLYMER KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2000-02-17 WO claimed
EP-0251732-B1 PROCESS FOR THE PREPARATION OF 2-HALOGENATED ERGOLINE DERIVATIVES RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1993-04-28 EP claimed
US-4816587-A Process for the preparation of 2-halogenated ergoline derivatives RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1989-03-28 US claimed
EP-0251732-A2 Process for the preparation of 2-halogenated ergoline derivatives RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1988-01-07 EP claimed
US-3980680-A Process for the preparation of 21-desoxy-17-acyloxy-4-pregnenes and of 21-iodo-21-desoxy-17-acyl oxy-4-pregnene intermediates useful therein SCHERING CORPORATION (US) 1976-09-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS HAO2, SCO2, SOD1 RAB9A 2640/4885MEN1 1632/4885KMT2A 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.