SCHEMBL874349

SCHEMBL874349

I[Si](I)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
ALDH1A1 P00352 5/20 0.35
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 3/20 0.32
ALOX12 P18054 2/20 0.32
HPGD P15428 2/20 0.32
NOTUM Q6P988 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
TSHR P16473 4/20 0.32
CA9 Q16790 3/20 0.32
TDP1 Q9NUW8 3/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA7 P43166 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL874968 0.79 ESR1 (0.36) ESR1ESR2ALDH1A1RAB9ANPC1
SCHEMBL873949 0.79 RAB9A (0.36) ESR1ESR2ALDH1A1RAB9ANPC1
SCHEMBL28072682 0.76 ESR1 (0.35) ESR1ESR2ALDH1A1RAB9ANPC1
SCHEMBL7665890 0.73 ESR1 (0.44) ESR1ESR2ALDH1A1RAB9ANPC1
SCHEMBL18108128 0.73 ALDH1A1 (0.35) ESR1ESR2ALDH1A1RAB9ANPC1
SCHEMBL8967403 0.73 ESR1 (0.44) ESR1ESR2ALDH1A1RAB9ANPC1
SCHEMBL18108506 0.73 TSHR (0.35) ESR1ESR2ALDH1A1RAB9ANPC1
SCHEMBL18108392 0.73 TSHR (0.35) ESR1ESR2ALDH1A1RAB9ANPC1
SCHEMBL18108178 0.73 ALDH1A1 (0.35) ESR1ESR2ALDH1A1RAB9ANPC1
SCHEMBL18108083 0.73 ALDH1A1 (0.35) ESR1ESR2ALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1939221-B1 A METHOD FOR PRODUCING FUNCTIONALIZED CIS-1,4POLYDIENES HAVING HIGH CIS-1,4-LINKAGE CONTENT AND HIGH FUNCTIONALITY BRIDGESTONE CORP (JP) 2017-10-18 EP claimed
US-7825201-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2010-11-02 US claimed
US-20090299019-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2009-12-03 US claimed
US-20080182954-A1 METHOD FOR PRODUCING FUNCTIONALIZED CIS-1,4-POLYDIENES HAVING HIGH CIS-1,4-LINKAGE CONTENT AND HIGH FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2008-07-31 US claimed
EP-1939221-A2 A method for producing functionalized cis-1,4polydienes having high cis-1,4-linkage content and high functionality Bridgestone Corporation (JP) 2008-07-02 EP claimed
EP-4737489-A1 CATALYST COMPOSITION PREPARATION METHOD AND CONJUGATED DIENE-BASED POLYMER PREPARATION METHOD LG CHEM, LTD. (KR) 2026-05-06 EP disclosed
US-12617879-B2 Neodymium-catalyzed conjugated diene-based polymer and rubber composition comprising same LG CHEM, LTD. (KR) 2026-05-05 US disclosed
US-12565546-B2 Imine group-containing novel compound, modified conjugated diene-based polymer including same, method for preparing the polymer, and rubber composition including the polymer LG CHEM, LTD. (KR) 2026-03-03 US disclosed
EP-4653477-A1 CONJUGATED DIENE-BASED POLYMER AND RUBBER COMPOSITION LG CHEM, LTD. (KR) 2025-11-26 EP disclosed
EP-4653475-A1 CONJUGATED DIENE-BASED POLYMER AND RUBBER COMPOSITION LG CHEM, LTD. (KR) 2025-11-26 EP disclosed
EP-4032921-B1 METHOD FOR PREPARING MODIFIED CONJUGATED DIENE-BASED POLYMER LG CHEMICAL LTD (KR) 2025-08-27 EP disclosed
EP-4600275-A1 CATALYST COMPOSITION PREPARATION METHOD AND CONJUGATED DIENE POLYMER PREPARATION METHOD LG CHEM, LTD. (KR) 2025-08-13 EP disclosed
EP-0547774-A1 Process for disproportionation of arylsilanes DOW CORNING CORPORATION (US) 1993-06-23 EP disclosed
EP-0539039-A1 Thermal disproportionation of arylhalosilanes DOW CORNING CORPORATION (US) 1993-04-28 EP disclosed
US-5175331-A Reacting silicon tetrafluoride with alkyl or aryl halide in presence of metallic aluminum catalyst; chlorination, bromination or iodination ETHYL CORPORATION (US) 1992-12-29 US disclosed
US-5138082-A Catalytic reaction of silicon tetrafluoride with organo-aluminum compound ETHYL CORPORATION (US) 1992-08-11 US disclosed
US-5136070-A Sodium borohydride catalyzed disproportionation of cycloorganosilanes DOW CORNING CORPORATION (US) 1992-08-04 US disclosed
US-5136071-A Reduces induction time DOW CORNING CORPORATION (US) 1992-08-04 US disclosed
US-5110974-A Thermal disproportionation of arylhalosilanes DOW CORNING CORPORATION (US) 1992-05-05 US disclosed
US-4751170-A Silylation method onto surface of polymer membrane and pattern formation process by the utilization of silylation method NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1988-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565546-B2 Imine group-containing novel compound, modified conjugated diene-based polymer including same, method for preparing the polymer, and rubber composition including the polymer CARM1, RIF1, UFM1 ESR1 3302/4885ESR2 2569/4885ALDH1A1 832/4885
US-12617879-B2 Neodymium-catalyzed conjugated diene-based polymer and rubber composition comprising same RPA1, RAD1, COL1A1 ESR1 2621/4885ESR2 2013/4885ALDH1A1 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.