Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20310 | 0.82 | F2 (0.50) | F2PRSS1PRSS2PRSS3CA1 | |
| Hydrochloric Acid SCHEMBL28479231 | 0.80 | F2 (0.49) | F2PRSS1PRSS2PRSS3CA1 | |
| Methylene Chloride SCHEMBL23923198 | 0.79 | F2 (0.45) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL20626670 | 0.74 | F2 (0.44) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL301212 | 0.70 | F2 (0.47) | F2PRSS1PRSS2PRSS3CA1 | |
| Trifluoroacetic Acid SCHEMBL8316154 | 0.69 | F2 (0.43) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL2678329 | 0.65 | CA1 (0.50) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL19309115 | 0.65 | CA2 (0.34) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL6911996 | 0.64 | RAPGEF4 (0.48) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL3445101 | 0.64 | RAPGEF4 (0.41) | RAPGEF4MAPTALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129836-A1 | Imidazole derivatives as PDE10A enzyme inhibitors | H. LUNDBECK A/S (DK) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129836-A1 | Imidazole derivatives as PDE10A enzyme inhibitors | PDE5A, PDE3A, PDE3B | F2 4053/4885PRSS1 1125/4885PRSS2 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.