Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24777730 | 0.89 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TSHRFFAR1HTR7 | |
| SCHEMBL2135627 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHRHTR7HSD17B10 | |
| SCHEMBL342130 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRCA12CA2 | |
| SCHEMBL29415443 | 0.81 | RAB9A (0.46) | ALDH1A1CYP3A4FFAR1LMNAMAPT | |
| SCHEMBL11879900 | 0.81 | FFAR1 (0.43) | ALDH1A1CYP3A4TSHRFFAR1THRA | |
| SCHEMBL22716240 | 0.81 | FOLH1 (0.39) | ALDH1A1TSHRFFAR1THRATHRB | |
| SCHEMBL2808540 | 0.81 | PTPN1 (0.46) | ALDH1A1CA12CA2CA9CA1 | |
| SCHEMBL2808504 | 0.81 | RAB9A (0.46) | ALDH1A1CYP3A4FFAR1LMNAMAPT | |
| SCHEMBL2804456 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1CYP3A4TSHRFFAR1LMNA | |
| SCHEMBL8740014 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387602-A1 | BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2022-12-08 | — | — | US | disclosed |
| EP-4031247-A1 | BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | Novartis AG (CH) | 2022-07-27 | — | — | EP | disclosed |
| CN-114521196-A | Bifunctional group degradation agent and use method thereof | 诺华股份有限公司 | 2022-05-20 | — | — | CN | disclosed |
| WO-2021053495-A1 | BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2021-03-25 | — | — | WO | disclosed |
| US-9701667-B2 | Coumarin-based fluorogenic agents and uses thereof for specific protein labelling | UNIVERSITY OF OTTAWA (CA) | 2017-07-11 | — | — | US | disclosed |
| US-20150316557-A1 | COUMARIN-BASED FLUOROGENIC AGENTS AND USES THEREOF FOR SPECIFIC PROTEIN LABELLING | UNIVERSITY OF OTTAWA (CA) | 2015-11-05 | — | — | US | disclosed |
| US-5668260-A | Tetrakisazo Compounds, the method of preparation thereof and the process of pyeing | HOECHT AKTIENGE SELLSCHAFT (DE) | 1997-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387602-A1 | BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | JMJD7, MDM2, IDE | ALDH1A1 2189/4885CYP3A4 2539/4885TSHR 2854/4885 |
| US-20150316557-A1 | COUMARIN-BASED FLUOROGENIC AGENTS AND USES THEREOF FOR SPECIFIC PROTEIN LABELLING | PFDN1, PFDN6, CDC73 | ALDH1A1 1274/4885CYP3A4 399/4885TSHR 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.