Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17423273 | 0.85 | NQO1 (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL222907 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| Water SCHEMBL7769205 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL28335934 | 0.75 | MAPT (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL29097636 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8688917 | 0.73 | CYP2D6 (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL14579662 | 0.72 | NQO1 (0.71) | ALDH1A1KDM4ENQO2NQO1MAPT | |
| Acridine SCHEMBL28113323 | 0.71 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL240664 | 0.71 | NQO2 (0.57) | ALDH1A1KMT2ASMN1; SMN2KDM4ENQO2 | |
| SCHEMBL29928420 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755457-A4 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0755457-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5523212-A | OXIDATION WITH PEROXIDE AND PEROXIDASE TO EXCITED ACRIDONE DERIVATIVE; DETECTING PROTEINS, HAPTENS, ANTIBODIES, ENZYMES | LUMIGEN, INC. (US) | 1996-06-04 | — | — | US | disclosed |
| WO-1995028495-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1995-10-26 | — | — | WO | disclosed |