SCHEMBL8740907

SCHEMBL8740907

CCOC(=O)c1[nH]c(C)c(CC)c1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.58
NPSR1 Q6W5P4 4/20 0.58
MAPT P10636 3/20 0.58
STAT1 P42224 1/20 0.58
ALDH1A1 P00352 5/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2C19 P33261 2/20 0.55
HPGD P15428 2/20 0.55
XBP1 P17861 1/20 0.55
POLB P06746 1/20 0.54
ATM Q13315 1/20 0.54
CYP2C9 P11712 1/20 0.51
NPC1 O15118 3/20 0.50
LMNA P02545 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
HTT P42858 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21480114 0.85 CYP1A2 (0.58) RAB9ANPSR1MAPTSTAT1ALDH1A1
SCHEMBL1126706 0.84 ALDH1A1 (0.62) RAB9ANPSR1MAPTALDH1A1CYP1A2
SCHEMBL1127132 0.83 ALDH1A1 (0.55) RAB9ANPSR1MAPTALDH1A1CYP1A2
SCHEMBL29757646 0.82 RAB9A (0.56) RAB9ANPSR1MAPTALDH1A1CYP1A2
SCHEMBL1126748 0.79 ALDH1A1 (0.56) RAB9ANPSR1MAPTALDH1A1CYP1A2
SCHEMBL24584793 0.79 ALDH1A1 (0.56) RAB9ANPSR1MAPTALDH1A1CYP1A2
SCHEMBL20568922 0.77 ALDH1A1 (0.55) RAB9ANPSR1MAPTALDH1A1CYP1A2
SCHEMBL20568240 0.77 ALDH1A1 (0.58) RAB9ANPSR1MAPTALDH1A1CYP1A2
SCHEMBL2956667 0.77 ALDH1A1 (0.73) MAPTALDH1A1CYP1A2CYP2C19HPGD
SCHEMBL4201730 0.76 CYP1A2 (0.67) RAB9ANPSR1MAPTSTAT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111606888-B Pyrrole derivative and preparation method and application thereof 中国药科大学 2023-08-18 CN disclosed
CN-111606888-A Pyrrole derivative and preparation method and application thereof 中国药科大学 2020-09-01 CN disclosed
EP-0684950-A4 CHEMICAL COMPOUNDS USEFUL IN PHOTODYNAMIC THERAPY AND PRODUCTION OF LASER LIGHT. BO DEKK VENTURES LTD (US) 1997-10-15 EP disclosed
EP-0684950-A1 CHEMICAL COMPOUNDS USEFUL IN PHOTODYNAMIC THERAPY AND PRODUCTION OF LASER LIGHT BO-DEKK VENTURES, LTD. (US) 1995-12-06 EP disclosed
US-5446157-A Boron difluoride compounds useful in photodynamic therapy and production of laser light BO-DEKK VENTURES, LTD. 1995-08-29 US disclosed
WO-1994019355-A1 CHEMICAL COMPOUNDS USEFUL IN PHOTODYNAMIC THERAPY AND PRODUCTION OF LASER LIGHT BO-DEKK VENTURES, LTD. (US) 1994-09-01 WO disclosed