Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167562 | 0.87 | TAAR1 (0.64) | TAAR1MAOB | |
| SCHEMBL2328953 | 0.84 | MEN1 (0.48) | TAAR1MAOAMAOB | |
| SCHEMBL10405439 | 0.82 | ALDH1A1 (0.56) | HTR2A | |
| SCHEMBL10405802 | 0.82 | TDP1 (0.46) | CALM1 | |
| SCHEMBL9833543 | 0.82 | CALM1 (0.41) | TAAR1CALM1 | |
| SCHEMBL9015403 | 0.82 | ALDH1A1 (0.56) | HTR2A | |
| SCHEMBL874531 | 0.81 | ALDH1A1 (0.47) | CALM1 | |
| SCHEMBL8087303 | 0.81 | NQO1 (0.54) | TAAR1MAOAHRH1HTR2A | |
| SCHEMBL2328648 | 0.81 | TAAR1 (0.73) | TAAR1MAOAMAOBCALM1 | |
| SCHEMBL10405522 | 0.81 | MEN1 (0.51) | CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | The Regents of the University of Michigan (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040527-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-03-29 | — | — | WO | disclosed |