SCHEMBL8741561

SCHEMBL8741561

CC(=O)C(CO)(CO)NCCCNC(CO)(CO)C(=O)C(=O)n1cc(C)nc1[N+](=O)[O-]

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MITF O75030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8565270 0.84 MITF (0.31) MITF
SCHEMBL6131607 0.69 MITF (0.40) MITF
SCHEMBL8557711 0.65 LMNA (0.39)
SCHEMBL28888792 0.65 MITF (0.51) MITF
SCHEMBL8564389 0.62 SMN1; SMN2 (0.34)
SCHEMBL8564887 0.58 TAAR1 (0.35)
SCHEMBL8565364 0.58 LMNA (0.39)
SCHEMBL8741531 0.58 LMNA (0.36)
SCHEMBL8557859 0.57 LMNA (0.35)
SCHEMBL6131588 0.56 MITF (0.44) MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5688487-A Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety BRACCO INTERNATIONAL B.V. (NL) 1997-11-18 US disclosed