Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875385 | 0.87 | MAPT (0.40) | CHRNA7MAPTLMNAMEN1KMT2A | |
| SCHEMBL874210 | 0.78 | MAPT (0.40) | CHRNA7MAPTMEN1KMT2ANPC1 | |
| SCHEMBL874082 | 0.77 | MAPT (0.38) | CHRNA7MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL874083 | 0.77 | KDM4E (0.38) | CHRNA7MAPTLMNAMEN1KMT2A | |
| SCHEMBL874570 | 0.76 | MOK (0.43) | CHRNA7MAPTMEN1KMT2ANPC1 | |
| SCHEMBL874571 | 0.75 | MAPT (0.38) | CHRNA7MAPTLMNAMEN1KMT2A | |
| SCHEMBL874837 | 0.75 | KMT2A (0.37) | CHRNA7MAPTKMT2ACYP2C9NPC1 | |
| SCHEMBL3050177 | 0.74 | POLB (0.55) | MEN1KMT2ANAMPTALDH1A1POLB | |
| SCHEMBL874339 | 0.74 | MKNK1 (0.39) | CHRNA7MAPTNPC1RAB9AKDM4E | |
| SCHEMBL874300 | 0.73 | MAPT (0.37) | MAPTLMNAMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |