Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873721 | 0.90 | BCHE (0.39) | BCHEACHECHRNA7NAMPTRAB9A | |
| SCHEMBL873820 | 0.87 | ATR (0.46) | MEN1KMT2ACHRNA7NAMPTNPSR1 | |
| SCHEMBL873584 | 0.85 | KMT2A (0.40) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL874281 | 0.83 | RAB9A (0.40) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL874835 | 0.82 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL875500 | 0.79 | ATR (0.41) | CHRNA7NAMPTSYKNPSR1 | |
| SCHEMBL873865 | 0.79 | NAMPT (0.42) | BCHEACHEALDH1A1GAACHRNA7 | |
| SCHEMBL873821 | 0.78 | NAMPT (0.39) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL874291 | 0.78 | CHRNA7 (0.39) | BCHEACHEKMT2AMAPTCHRNA7 | |
| SCHEMBL874482 | 0.77 | CHRM4 (0.42) | BCHEACHEMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |