Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873722 | 0.91 | RXFP1 (0.38) | RAB9ARXFP1CHRNA7SLC6A9SLC6A5 | |
| SCHEMBL873821 | 0.86 | NAMPT (0.39) | RAB9ACHRNA7ALDH1A1MAPTMEN1 | |
| SCHEMBL874280 | 0.83 | BCHE (0.39) | RAB9ACHRNA7ALDH1A1MAPTMEN1 | |
| SCHEMBL874835 | 0.81 | MEN1 (0.43) | RAB9ACHRNA7ALDH1A1MAPTMEN1 | |
| SCHEMBL873866 | 0.79 | CHRNA7 (0.42) | RAB9ARXFP1CHRNA7ALDH1A1GAA | |
| SCHEMBL873820 | 0.78 | ATR (0.46) | CHRNA7MEN1KMT2ANPSR1NAMPT | |
| SCHEMBL875501 | 0.78 | CHRNA7 (0.40) | CHRNA7MAPTSYKNAMPTSMN1; SMN2 | |
| SCHEMBL874483 | 0.78 | RAB9A (0.40) | RAB9ARXFP1CHRNA7SLC6A9SLC6A5 | |
| SCHEMBL873584 | 0.78 | KMT2A (0.40) | RAB9ARXFP1ALDH1A1MAPTMEN1 | |
| SCHEMBL874083 | 0.77 | KDM4E (0.38) | RAB9ARXFP1CHRNA7ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |