Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874281 | 0.91 | RAB9A (0.40) | RXFP1CHRNA7RAB9ASLC6A9SLC6A5 | |
| SCHEMBL875501 | 0.87 | CHRNA7 (0.40) | CHRNA7TRPV1NAMPTSYKSMN1; SMN2 | |
| SCHEMBL882629 | 0.84 | CHRNA7 (0.42) | CHRNA7RAB9ATRPV1NAMPTSYK | |
| SCHEMBL873877 | 0.83 | CHRNA7 (0.42) | CHRNA7RAB9ATRPV1NAMPTSYK | |
| SCHEMBL873721 | 0.82 | BCHE (0.39) | CHRNA7RAB9ATRPV1NAMPTSYK | |
| SCHEMBL874291 | 0.80 | CHRNA7 (0.39) | RXFP1CHRNA7RAB9ATRPV1NAMPT | |
| SCHEMBL873866 | 0.80 | CHRNA7 (0.42) | RXFP1CHRNA7RAB9ANAMPTSMN1; SMN2 | |
| SCHEMBL875500 | 0.80 | ATR (0.41) | CHRNA7NAMPTSYK | |
| SCHEMBL874483 | 0.79 | RAB9A (0.40) | RXFP1CHRNA7RAB9ASLC6A9TRPV1 | |
| SCHEMBL874083 | 0.78 | KDM4E (0.38) | RXFP1CHRNA7RAB9ATRPV1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |