Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | UGCG | Q16739 | 2/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743569 | 0.77 | FGFR1 (0.42) | FGFR1SLC22A6HDAC1HDAC6EP300 | |
| SCHEMBL14639387 | 0.73 | FGFR1 (0.42) | FGFR1SLC22A6HDAC1HDAC6EP300 | |
| SCHEMBL13947 | 0.72 | EP300 (0.36) | MAOAMAOBFGFR1SLC22A6EP300 | |
| SCHEMBL8743576 | 0.72 | MAOA (0.36) | MAOAMAOBFGFR1SLC22A6KDM4E | |
| SCHEMBL9836693 | 0.72 | MAPK1 (0.52) | MAOAMAOBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL248682 | 0.72 | EP300 (0.49) | MAPK14KDM4EEP300ALDH1A1HTT | |
| SCHEMBL9652263 | 0.71 | FGFR1 (0.43) | FGFR1SLC22A6MAPK14EP300TSHR | |
| SCHEMBL8743582 | 0.71 | MAOA (0.37) | MAOAMAOBFGFR1SLC22A6HDAC3 | |
| SCHEMBL16978939 | 0.70 | FGFR1 (0.42) | FGFR1SLC22A6EP300 | |
| SCHEMBL9836818 | 0.70 | TSHR (0.48) | KDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335770-B1 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMA INC (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0339161-A1 | Novel fluorophosphonate nucleotide derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-11-02 | — | — | EP | disclosed |
| EP-0335770-A2 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1989-10-04 | — | — | EP | disclosed |