Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743559 | 0.85 | HDAC1 (0.36) | HDAC6HDAC1HDAC4HDAC2HSP90AA1 | |
| SCHEMBL10996722 | 0.77 | HDAC1 (0.47) | HDAC6HDAC1HDAC4HDAC2HSP90AA1 | |
| SCHEMBL8743576 | 0.74 | MAOA (0.36) | MAOAMAOBALDH1A1CYP3A4PDE2A | |
| SCHEMBL9663142 | 0.70 | HDAC1 (0.46) | HDAC6HDAC1HDAC4HDAC2HSP90AA1 | |
| SCHEMBL8816230 | 0.70 | HDAC1 (0.35) | HDAC6HDAC1HDAC4HDAC2HSP90AA1 | |
| SCHEMBL8743585 | 0.70 | HDAC6 (0.43) | HDAC6HDAC1HDAC4HDAC2HSP90AA1 | |
| SCHEMBL10510295 | 0.69 | HDAC1 (0.44) | HDAC6HDAC1HDAC4HDAC2HSP90AA1 | |
| SCHEMBL7617492 | 0.69 | HDAC1 (0.45) | HDAC6HDAC1HDAC4HDAC2HSP90AA1 | |
| SCHEMBL13976351 | 0.68 | HSP90AB1 (0.38) | HDAC6HDAC1HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL8743537 | 0.68 | MAOB (0.34) | MAOAMAOBPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335770-B1 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMA INC (US) | 1997-01-15 | — | — | EP | disclosed |