Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trinitrophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 11/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | TTR | P02766 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trinitrophenol SCHEMBL2260890 | 1.00 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL2260895 | 1.00 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL11362471 | 1.00 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL253750 | 0.98 | GPR35 (0.79) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL8744 | 0.98 | GPR35 (0.79) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL1692116 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL2197458 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL18691159 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL9140811 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL2218625 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 606 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260110607-A1 | TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES WITH MINIMIZED FALSE POSITIVES | ALTI LLC (US) | 2026-04-23 | — | — | US | claimed |
| US-12517047-B2 | Transport and detection of explosive samples | ALTI LLC (US) | 2026-01-06 | — | — | US | claimed |
| US-20250237601-A1 | TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES | ALTI LLC | 2025-07-24 | — | — | US | claimed |
| CN-119330384-A | Preparation method of layered high specific surface area hydroxyl alumina nano material and catalyst thereof | 闽南师范大学 | 2025-01-21 | — | — | CN | claimed |
| CN-118324694-A | Fluorescent compound for rapidly detecting explosive as well as preparation method and application thereof | 湖南华南光电科技股份有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-110491674-B | Solid-liquid mixed aluminum electrolytic capacitor and preparation method thereof | 上海永铭电子股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-216696028-U | Safe metal material friction spark testing arrangement | 中国矿业大学 | 2022-06-07 | — | — | CN | claimed |
| US-10968147-B2 | Pyrotechnic agent | RUAG AMMOTEC GMBH (DE) | 2021-04-06 | — | — | US | claimed |
| US-20200094301-A1 | Heat-Enhanced Treatment Of Energetic Compounds In Contaminated Soil, Sediment And/Or Water | CDM SMITH INC. | 2020-03-26 | — | — | US | claimed |
| CN-207800373-U | High-energized solid-liquid mixed aluminum electrolytic capacitor | 深圳江浩电子有限公司 | 2018-08-31 | — | — | CN | claimed |
| EP-0430462-A2 | Improved melt cast explosives | EXPLOSIVE RESEARCH & DEVELOPMENT CORPORATION (US) | 1991-06-05 | — | — | EP | claimed |
| US-4985093-A | TNT, LOW MOLECULAR WEIGHT BINDER, POLYURETHANE, CROSSLINKING | EXPLOSIVE RESEARCH AND DEVELOPMENT CORPORATION (US) | 1991-01-15 | — | — | US | claimed |
| EP-0350029-A2 | Biconvex polymer lenses and their production and use | CESKOSLOVENSKA AKADEMIE VED (CS) | 1990-01-10 | — | — | EP | claimed |
| US-4544666-A | COMPLEXING AMMONIUM FORMATE, PICRIC ACID AND TANNIC ACID IN PRESENCE OF SURFACTANT | PHYTON/AG, INC. (US) | 1985-10-01 | — | — | US | claimed |
| US-4455150-A | Chemically enhanced combustion of water-slurry fuels | OLEN KENNETH R | 1984-06-19 | — | — | US | claimed |
| US-4402268-A | Electric primer for caseless propellant charges | Usel, Hubert (AU) | 1983-09-06 | — | — | US | claimed |
| US-4239073-A | BINDER SYNERGISTICALLY REACTS WITH THE OXIDIZER | THIOKOL CORPORATION (US) | 1980-12-16 | — | — | US | claimed |
| US-4124663-A | Continuous process for pelleting explosive compositions | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1978-11-07 | — | — | US | claimed |
| US-4025591-A | ACRYLIC ESTER CURING MONOMER, ORGANIC PEROXIDE CATALYST | JET RESEARCH CENTER, INC. (US) | 1977-05-24 | — | — | US | claimed |
| US-3957550-A | EXPLOSIVES, LIQUID FUELS, OXIDIZERS | THIOKOL CORPORATION (US) | 1976-05-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260110607-A1 | TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES WITH MINIMIZED FALSE POSITIVES | TES, TNPO1, SLC2A1 | GPR35 1862/4885ALDH1A1 4406/4885HPGD 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.