Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922666 | 0.77 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2TDP1MAPT | |
| SCHEMBL8744025 | 0.77 | KDM4E (0.46) | NPC1RAB9AMAOAMAOBSLC22A2 | |
| SCHEMBL3921739 | 0.77 | TSHR (0.40) | SLC22A2TDP1ALDH1A1TSHRCASP1 | |
| SCHEMBL11690323 | 0.77 | ALDH1A1 (0.42) | NPC1RAB9ASMN1; SMN2HPGDMAOA | |
| SCHEMBL8744066 | 0.77 | S100B (0.39) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL8743958 | 0.77 | ALDH1A1 (0.49) | SMN1; SMN2HPGDMAOAMAOBHTR3E | |
| SCHEMBL8743938 | 0.77 | MAOB (0.41) | NPC1RAB9ASMN1; SMN2HPGDMAOA | |
| SCHEMBL570653 | 0.76 | MEN1 (0.41) | NPC1RAB9ASMN1; SMN2MAOAMAOB | |
| SCHEMBL8743913 | 0.75 | HPGD (0.34) | NPC1RAB9ASMN1; SMN2HPGDHTR3E | |
| SCHEMBL8743975 | 0.75 | HTR3E (0.44) | NPC1RAB9ASMN1; SMN2HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618980-A | DEHYDROGENATING N-CYCLOHEXYLIDENEAMINO COMPOUND IN PRESENCE OF HYDROGEN TRANSFER CATALYST AND HYDROGEN ACCEPTOR AND ALKALI OR ALKALINE EARTH METAL COMPOUND COCATALYST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-04-08 | — | — | US | disclosed |
| EP-0588060-B1 | Method for preparing aromatic secondary amino compound | MITSUI TOATSU CHEMICALS (JP) | 1997-04-02 | — | — | EP | disclosed |
| EP-0753505-A2 | Method for preparing aromatic secondary amino compound | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5536878-A | HYDROGEN ACCEPTOR | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5382690-A | Method for preparing aromatic secondary amino compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0588060-A2 | Method for preparing aromatic secondary amino compound | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-4281195-A | Process for the preparation of Schiff's bases by the reaction of aromatic amines with ketones | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-28 | — | — | US | disclosed |
| EP-0014264-A1 | Process for the production of Schiff bases by reaction of aromatic amines with aliphatic ketones in the presence of catalysts | BAYER AG (DE) | 1980-08-20 | — | — | EP | disclosed |