Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17053451 | 0.97 | ALDH1A1 (0.41) | MEN1KMT2ARAB9AGAANPC1 | |
| Aniline SCHEMBL7809682 | 0.89 | TSHR (0.44) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL9359959 | 0.87 | ALDH1A1 (0.39) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL8744041 | 0.82 | LTA4H (0.44) | ALDH1A1KDM4ETSHRMAOA | |
| SCHEMBL8744066 | 0.76 | S100B (0.39) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL8922666 | 0.76 | MAPT (0.44) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL8744002 | 0.76 | NPC1 (0.39) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL11690323 | 0.76 | ALDH1A1 (0.42) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL8744025 | 0.76 | KDM4E (0.46) | KMT2ARAB9AGAANPC1ALDH1A1 | |
| SCHEMBL3921739 | 0.76 | TSHR (0.40) | ALDH1A1TDP1TSHRCASP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907214-B | Preparation method of dicyclohexylamine | 万华化学集团股份有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-114907214-A | Preparation method of dicyclohexylamine | 万华化学集团股份有限公司 | 2022-08-16 | — | — | CN | claimed |
| US-9701617-B2 | Process for producing diamines and polyamines of the diphenylmethane series | COVESTRO DEUTSCHLAND AG (DE) | 2017-07-11 | — | — | US | claimed |
| EP-2103595-B1 | Method for producing di and polyamines of diphenylmethane series | COVESTRO DEUTSCHLAND AG (DE) | 2017-04-19 | — | — | EP | claimed |
| EP-2601170-A1 | PROCESS FOR THE PRODUCTION OF HIGHLY PURE DICYCLOHEXYLAMINE FROM BY-PRODUCTS RESULTING FROM THE PRODUCTON OF CYCLOHEXYLAMINE | Duslo, A.S. (SK) | 2013-06-12 | — | — | EP | claimed |
| WO-2012018310-A1 | PROCESS FOR THE PRODUCTION OF HIGHLY PURE DICYCLOHEXYLAMINE FROM BY-PRODUCTS RESULTING FROM THE PRODUCTON OF CYCLOHEXYLAMINE | DUSLO, A.S. (SK) | 2012-02-09 | — | — | WO | claimed |
| US-20090240077-A1 | PROCESS FOR PRODUCING DIAMINES AND POLYAMINES OF THE DIPHENYLMETHANE SERIES | BAYER MATERIALSCIENCE AG (DE) | 2009-09-24 | — | — | US | claimed |
| EP-2103595-A1 | Method for producing di and polyamines of diphenylmethane series | Bayer MaterialScience AG (DE) | 2009-09-23 | — | — | EP | claimed |
| EP-0501265-B1 | Method for the production of a mixture of cyclohexyl amine and dicyclohexyl amine using a noble metal supported catalyst | BAYER AG (DE) | 1994-11-02 | — | — | EP | claimed |
| EP-0494455-B1 | Process for the preparation of diphenylamines | BAYER AG (DE) | 1994-07-27 | — | — | EP | claimed |
| US-5322965-A | Hydrogenation of optionally substituted aniline with palladium and ruthenium on niobic acid support | BAYER AKTIENGESELLSCHAFT (DE) | 1994-06-21 | — | — | US | claimed |
| US-5247009-A | Reacted with an imine and an acid halide, tires | NIPPON ZEON CO., LTD. (JP) | 1993-09-21 | — | — | US | claimed |
| US-5196592-A | Rhodium containing dehydrogenation catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | claimed |
| EP-0501265-A1 | Method for the production of a mixture of cyclohexyl amine and dicyclohexyl amine using a noble metal supported catalyst | BAYER AG (DE) | 1992-09-02 | — | — | EP | claimed |
| EP-0494455-A1 | Process for the preparation of diphenylamines | BAYER AG (DE) | 1992-07-15 | — | — | EP | claimed |
| US-4677153-A | REACTING WITH AN ACYL HALIDE AND | NIPPON ZEON CO., LTD. (JP) | 1987-06-30 | — | — | US | claimed |
| US-4057581-A | CATALYTIC DEHYDROGENATION, NICKEL-CHROMIUM-MANGANESE OR COPPER OR ALUMINUM CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | claimed |
| JP-11343344-A | — | — | None | — | — | JP | disclosed |
| US-3984544-A | Retinoic acid esters of steroids of the pregnane series, their use in the treatment of acne and pharmaceutical formulations useful therefor | SCHERING CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |
| US-3932388-A | STEROIDS, GLUCOCORTICOID ACITIVITY | SCHERING CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240077-A1 | PROCESS FOR PRODUCING DIAMINES AND POLYAMINES OF THE DIPHENYLMETHANE SERIES | SRM, PNMT, DDT | MEN1 2360/4885KMT2A 383/4885RAB9A 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.