SCHEMBL8744170

SCHEMBL8744170

O=C(F)CCCCC(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.34
CES1 P23141 5/20 0.33
CES2 O00748 3/20 0.33
OXER1 Q8TDS5 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALOX5 P09917 1/20 0.32
CYSLTR2 Q9NS75 1/20 0.30
CYSLTR1 Q9Y271 1/20 0.30
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20543472 0.97 FAAH (0.37) FAAHCES1CES2OXER1MEN1
SCHEMBL28405229 0.97 FAAH (0.37) FAAHCES1CES2OXER1MEN1
SCHEMBL28403565 0.97 FAAH (0.37) FAAHCES1CES2OXER1MEN1
SCHEMBL20543468 0.97 FAAH (0.37) FAAHCES1CES2OXER1MEN1
SCHEMBL8743995 0.92 FAAH (0.31) FAAHCES1CES2OXER1MEN1
SCHEMBL1648852 0.81 FAAH (0.36) FAAHCES1CES2OXER1MEN1
SCHEMBL8415757 0.80
SCHEMBL9620523 0.80 LMNA (0.44) FAAHCES1CES2LMNA
SCHEMBL866444 0.79 FAAH (0.34) FAAHCES1CES2OXER1MEN1
SCHEMBL866445 0.79 LMNA (0.58) OXER1MEN1KMT2AHSD17B10ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0753085-A1 PROCESS FOR PREPARING BRANCHED PERFLUOROCHEMICALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-15 EP disclosed
WO-1995026429-A1 PROCESS FOR PREPARING BRANCHED PERFLUOROCHEMICALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-10-05 WO disclosed