Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.40 |
| ▸ | TK2 | O00142 | 2/20 | 0.38 |
| ▸ | TK1 | P04183 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694341 | 0.83 | TK1 (0.43) | RNASE1TK1 | |
| SCHEMBL5148089 | 0.83 | RNASE1 (0.46) | RNASE1TK2TK1 | |
| SCHEMBL6536213 | 0.80 | TK1 (0.42) | TK1 | |
| SCHEMBL6923545 | 0.79 | RNASE1 (0.41) | RNASE1TK2TK1 | |
| SCHEMBL6923541 | 0.79 | RNASE1 (0.41) | RNASE1TK2TK1 | |
| SCHEMBL28239487 | 0.79 | TK1 (0.41) | TK1 | |
| SCHEMBL27651863 | 0.79 | TK1 (0.41) | TK2TK1 | |
| SCHEMBL28293851 | 0.79 | TK1 (0.39) | RNASE1TK1 | |
| SCHEMBL29927067 | 0.79 | RNASE1 (0.39) | RNASE1TK2TK1 | |
| SCHEMBL17224727 | 0.78 | TK1 (0.39) | RNASE1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753002-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026972-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1995-10-12 | — | — | WO | disclosed |