Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744397 | 0.86 | GNAO1 (0.50) | ALOX15GNAO1GNAI3GNAI1 | |
| SCHEMBL8744444 | 0.81 | ALOX15 (0.39) | ALOX15GNAO1GNAI3GNAI1POLB | |
| SCHEMBL23594086 | 0.81 | GNAO1 (0.40) | GNAO1GNAI3GNAI1HRH3HRH1 | |
| SCHEMBL20812161 | 0.80 | CYP1A2 (0.43) | ALOX15GNAO1GNAI3GNAI1SIGMAR1 | |
| SCHEMBL20812167 | 0.80 | CYP1A2 (0.43) | ALOX15GNAO1GNAI3GNAI1SIGMAR1 | |
| SCHEMBL20811564 | 0.80 | CYP1A2 (0.43) | ALOX15GNAO1GNAI3GNAI1SIGMAR1 | |
| SCHEMBL20805134 | 0.80 | CYP1A2 (0.43) | ALOX15GNAO1GNAI3GNAI1SIGMAR1 | |
| SCHEMBL13602675 | 0.79 | GNAO1 (0.37) | GNAO1GNAI3GNAI1HRH3HRH1 | |
| SCHEMBL20805132 | 0.79 | CYP1A2 (0.44) | ALOX15GNAO1GNAI3GNAI1SIGMAR1 | |
| SCHEMBL8744370 | 0.75 | NCF1 (0.35) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614534-A | Derivatives of β, β-dimethyl-4-piperidineethanamine as inhibitors of the cholesterol biosynthesis | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-03-25 | — | — | US | disclosed |
| EP-0699187-B1 | BETA,BETA-DIMETHYL-4-PIPERIDINEETHANAMINE DERIVATIVES AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS | FOURNIER IND & SANTE (FR) | 1997-01-22 | — | — | EP | disclosed |