Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942538 | 0.82 | GNAI3 (0.35) | HSD17B10FPR3FPR2OPRL1HTR4 | |
| SCHEMBL8744415 | 0.74 | ITGB3 (0.34) | ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8972354 | 0.71 | TP53 (0.45) | TP53SMN1; SMN2ALDH1A1HSD17B10FPR3 | |
| Hydrochloric Acid SCHEMBL8972193 | 0.71 | TP53 (0.44) | TP53SMN1; SMN2ALDH1A1HSD17B10FPR3 | |
| SCHEMBL24703425 | 0.70 | ALDH1A1 (0.45) | TP53SMN1; SMN2ALDH1A1FPR3FPR2 | |
| SCHEMBL24703504 | 0.70 | ALDH1A1 (0.40) | TP53SMN1; SMN2ALDH1A1OPRL1HTR4 | |
| SCHEMBL24703447 | 0.69 | ALDH1A1 (0.43) | TP53SMN1; SMN2ALDH1A1HSD17B10FPR3 | |
| SCHEMBL24703406 | 0.69 | SMN1; SMN2 (0.54) | TP53SMN1; SMN2ALDH1A1HSD17B10FPR3 | |
| SCHEMBL28277522 | 0.69 | ALDH1A1 (0.56) | TP53SMN1; SMN2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL24703545 | 0.68 | SMN1; SMN2 (0.44) | TP53SMN1; SMN2ALDH1A1HSD17B10FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614534-A | Derivatives of β, β-dimethyl-4-piperidineethanamine as inhibitors of the cholesterol biosynthesis | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-03-25 | — | — | US | disclosed |
| EP-0699187-B1 | BETA,BETA-DIMETHYL-4-PIPERIDINEETHANAMINE DERIVATIVES AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS | FOURNIER IND & SANTE (FR) | 1997-01-22 | — | — | EP | disclosed |