Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744396 | 0.82 | TP53 (0.44) | FPR3FPR2OPRL1HTR4HSD17B10 | |
| SCHEMBL25108944 | 0.72 | SIGMAR1 (0.42) | GNAI3GNAO1GNAI1CHRM4OPRL1 | |
| SCHEMBL25024081 | 0.69 | GNAO1 (0.45) | GNAI3GNAO1GNAI1BCHECHRM2 | |
| SCHEMBL21658978 | 0.68 | KCNH2 (0.32) | BCHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21106038 | 0.68 | SIGMAR1 (0.36) | GNAI3GNAO1GNAI1OPRL1 | |
| SCHEMBL26492376 | 0.68 | GNAO1 (0.45) | GNAI3GNAO1GNAI1CHRM2CHRM4 | |
| SCHEMBL26407146 | 0.68 | GNAO1 (0.41) | GNAI3GNAO1GNAI1 | |
| SCHEMBL23261538 | 0.68 | PIK3CD (0.36) | — | |
| SCHEMBL25728028 | 0.67 | GNAO1 (0.37) | GNAI3GNAO1GNAI1BCHE | |
| SCHEMBL8972506 | 0.67 | GNAI3 (0.37) | GNAI3GNAO1GNAI1BCHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699187-A1 | DERIVATIVES OF -g(b), -g(b)-DIMETHYL-4-PIPERIDINEETHANAMINE AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS | FOURNIER IND & SANTE (FR) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994026713-A1 | DERIVATIVES OF β, β-DIMETHYL-4-PIPERIDINEETHANAMINE AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS | FOURNIER INDUSTRIE ET SANTE (FR) | 1994-11-24 | — | — | WO | disclosed |