Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594200 | 1.00 | ELANE (0.48) | ELANEMETAP2MAPTPPARGPPARA | |
| SCHEMBL8744709 | 0.89 | ACE (0.55) | PPARGPPARAACETDP1SLC10A1 | |
| SCHEMBL8744713 | 0.89 | ACE (0.55) | PPARGPPARAACETDP1SLC10A1 | |
| SCHEMBL9594563 | 0.86 | TACR1 (0.57) | TACR1TP53MEN1KMT2A | |
| SCHEMBL8744805 | 0.86 | TACR1 (0.57) | TACR1TP53MEN1KMT2A | |
| SCHEMBL8744728 | 0.82 | USP2 (0.39) | KMT2A | |
| SCHEMBL9595916 | 0.82 | USP2 (0.39) | KMT2A | |
| SCHEMBL2238427 | 0.76 | METAP2 (0.53) | ELANEMETAP2PPARGPPARAACE | |
| SCHEMBL8458627 | 0.75 | METAP2 (0.50) | ELANEMETAP2PPARGPPARAACE | |
| SCHEMBL8458621 | 0.75 | METAP2 (0.50) | ELANEMETAP2PPARGPPARAACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |