Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | C1R | P00736 | 1/20 | 0.40 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594623 | 1.00 | KMT2A (0.44) | KMT2AALDH1A1SLC22A12POLBHPGD | |
| SCHEMBL8744750 | 0.90 | ALDH1A1 (0.48) | KMT2AALDH1A1SLC22A12POLBHPGD | |
| SCHEMBL9595704 | 0.90 | ALDH1A1 (0.48) | KMT2AALDH1A1SLC22A12POLBHPGD | |
| SCHEMBL9594560 | 0.86 | KMT2A (0.47) | KMT2AALDH1A1SLC22A12POLBHPGD | |
| SCHEMBL8744777 | 0.86 | KMT2A (0.47) | KMT2AALDH1A1SLC22A12POLBHPGD | |
| SCHEMBL8744816 | 0.83 | SDCBP (0.51) | KMT2AALDH1A1SLC22A12POLBHPGD | |
| SCHEMBL8744811 | 0.83 | SDCBP (0.51) | KMT2AALDH1A1SLC22A12POLBHPGD | |
| SCHEMBL8744783 | 0.82 | PPID (0.46) | KMT2AALDH1A1SLC22A12POLBHPGD | |
| SCHEMBL9594765 | 0.82 | PPID (0.46) | KMT2AALDH1A1SLC22A12POLBHPGD | |
| SCHEMBL4421840 | 0.81 | ALDH1A1 (0.50) | KMT2AALDH1A1POLBHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |