Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 3/20 | 0.51 |
| ▸ | SDC2 | P34741 | 3/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744816 | 1.00 | SDCBP (0.51) | SDCBPSDC2AKR1B1SLC22A12KMT2A | |
| SCHEMBL4435139 | 0.88 | MBTPS1 (0.47) | SDCBPSDC2SLC22A12KMT2AALDH1A1 | |
| SCHEMBL4435142 | 0.88 | MBTPS1 (0.47) | SDCBPSDC2SLC22A12KMT2AALDH1A1 | |
| SCHEMBL8744735 | 0.87 | PYGL (0.47) | AKR1B1SLC22A12KMT2AALDH1A1HPGD | |
| SCHEMBL8744730 | 0.87 | PYGL (0.47) | AKR1B1SLC22A12KMT2AALDH1A1HPGD | |
| SCHEMBL8744794 | 0.84 | AKR1B1 (0.53) | AKR1B1SLC22A12KMT2AALDH1A1HPGD | |
| SCHEMBL8744800 | 0.84 | AKR1B1 (0.53) | AKR1B1SLC22A12KMT2AALDH1A1HPGD | |
| SCHEMBL10308411 | 0.83 | SDCBP (0.44) | SDCBPSDC2AKR1B1SLC22A12KMT2A | |
| SCHEMBL12836919 | 0.83 | SDCBP (0.44) | SDCBPSDC2AKR1B1SLC22A12KMT2A | |
| SCHEMBL8744727 | 0.83 | KMT2A (0.44) | AKR1B1SLC22A12KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |