Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844162 | 0.87 | CNR2 (0.38) | CNR2CNR1ALDH1A1LMNAMAPT | |
| SCHEMBL9369273 | 0.78 | NLRP3 (0.37) | RORCALDH1A1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL9368867 | 0.77 | HPGD (0.40) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL9321131 | 0.76 | CA12 (0.40) | CNR2ABCC1CA12CA1CA2 | |
| SCHEMBL9371953 | 0.76 | NLRP3 (0.35) | RORCALDH1A1LMNATDP1MAPT | |
| SCHEMBL8985655 | 0.74 | CHRNB2 (0.47) | ALDH1A1LMNATDP1MAPTCHRNB2 | |
| SCHEMBL9368050 | 0.74 | NLRP3 (0.34) | RORCALDH1A1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL8744754 | 0.74 | NLRP3 (0.34) | RORCCNR2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9368573 | 0.74 | TDP1 (0.38) | ALDH1A1TDP1SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL9318604 | 0.73 | EPHX2 (0.41) | CNR2CNR1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |