Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744763 | 0.87 | RORC (0.39) | CNR2CNR1TSHRHTR2AMDM2 | |
| SCHEMBL6531075 | 0.74 | LMNA (0.40) | TSHRMDM2TP53SMN1; SMN2LMNA | |
| SCHEMBL8744741 | 0.72 | KDM4E (0.33) | TSHRSMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL6533143 | 0.71 | ALDH1A1 (0.39) | TSHRMDM2TP53SMN1; SMN2LMNA | |
| SCHEMBL9594867 | 0.70 | ALDH1A1 (0.39) | TSHRHTR2AHTR2CHTR2BTP53 | |
| SCHEMBL9555055 | 0.68 | ALDH1A1 (0.50) | CNR2TSHRTP53SMN1; SMN2LMNA | |
| SCHEMBL9321131 | 0.68 | CA12 (0.40) | CNR2TP53SMN1; SMN2 | |
| SCHEMBL7801107 | 0.67 | ALDH1A1 (0.43) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL7402365 | 0.67 | ALDH1A1 (0.43) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL2276227 | 0.67 | MT-CO2 (0.45) | CNR1TSHRHTR2AHTR2CMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |