Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 13/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645160 | 0.90 | IRAK4 (0.37) | IRAK4LMNAALDH1A1 | |
| SCHEMBL9782479 | 0.81 | ITGB1 (0.46) | LMNAALDH1A1 | |
| SCHEMBL27353938 | 0.77 | MGLL (0.37) | IRAK4IRAK1MGLLALDH1A1 | |
| SCHEMBL18289455 | 0.75 | KCNA5 (0.36) | MGLL | |
| SCHEMBL24335316 | 0.75 | IRAK4 (0.34) | IRAK4LMNA | |
| SCHEMBL22259093 | 0.75 | IRAK4 (0.34) | IRAK4KCNH2 | |
| SCHEMBL10372330 | 0.74 | ALDH1A1 (0.40) | IRAK4LMNAMGLLALDH1A1 | |
| SCHEMBL9646362 | 0.73 | TDP1 (0.39) | IRAK4MGLL | |
| SCHEMBL6825156 | 0.73 | DRD2 (0.38) | LMNA | |
| SCHEMBL10709560 | 0.73 | ITGB1 (0.39) | IRAK4LMNAIRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537606-B1 | Process for the preparation of 5-hydroxyethylpyrrolidones | BASF AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| US-5286875-A | Preparation of 5-hydroxyethylpyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | disclosed |
| EP-0537606-A1 | Process for the preparation of 5-hydroxyethylpyrrolidones | BASF Aktiengesellschaft (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0293740-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED LACTAMS | BASF Aktiengesellschaft (DE) | 1992-12-02 | — | — | EP | disclosed |
| US-4874865-A | Preparation of substituted lactams | BASF AKTIENGESELLSCHAFT (DE) | 1989-10-17 | — | — | US | disclosed |
| EP-0293740-A2 | Process for the preparation of substituted lactams | BASF Aktiengesellschaft (DE) | 1988-12-07 | — | — | EP | disclosed |