Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | BCL2 | P10415 | 4/20 | 0.52 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137691 | 0.88 | BCL2 (0.57) | KDM4EALDH1A1SIGMAR1HTR7BCL2 | |
| SCHEMBL588394 | 0.87 | SIGMAR1 (0.67) | KDM4EALDH1A1SIGMAR1HTR7BCL2 | |
| SCHEMBL8744977 | 0.86 | KDM4E (0.57) | KDM4EALDH1A1SIGMAR1HTR7BCL2 | |
| Hydrochloric Acid SCHEMBL587708 | 0.85 | SIGMAR1 (0.65) | KDM4EALDH1A1SIGMAR1HTR7BCL2 | |
| SCHEMBL8745021 | 0.84 | SIGMAR1 (0.65) | KDM4EALDH1A1SIGMAR1FAAHSMN1; SMN2 | |
| SCHEMBL2116073 | 0.84 | HTR7 (0.53) | KDM4EALDH1A1HTR7BCL2BAK1 | |
| SCHEMBL1958329 | 0.83 | HTR7 (0.55) | KDM4EALDH1A1SIGMAR1HTR7BCL2 | |
| SCHEMBL9178963 | 0.81 | CACNA1G (0.53) | HTR7BCL2BAK1BCL2L1FFAR1 | |
| SCHEMBL9184331 | 0.80 | HTR7 (0.53) | KDM4EALDH1A1HTR7BCL2BAK1 | |
| SCHEMBL1138135 | 0.80 | HTR7 (0.60) | KDM4EALDH1A1SIGMAR1HTR7BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |