Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8745012 | 0.99 | HTR7 (0.64) | HTR7HTTNPC1MAPTRAB9A | |
| SCHEMBL8111511 | 0.86 | HTT (0.77) | HTR7HTTNPC1MAPTRAB9A | |
| SCHEMBL9080030 | 0.85 | HTR1A (0.61) | HTR7HTTKDM4ESMN1; SMN2DRD4 | |
| SCHEMBL22418861 | 0.83 | HTT (0.70) | HTR7HTTNPC1MAPTRAB9A | |
| SCHEMBL13219071 | 0.83 | ALDH1A1 (0.74) | HTR7HTTNPC1MAPTRAB9A | |
| SCHEMBL8251966 | 0.81 | MAPT (0.66) | HTR7HTTNPC1MAPTRAB9A | |
| SCHEMBL10796159 | 0.81 | HTT (0.59) | HTR7HTTNPC1MAPTRAB9A | |
| SCHEMBL5174282 | 0.80 | NPSR1 (0.71) | HTTMAPTKDM4EDRD4ALDH1A1 | |
| SCHEMBL8691440 | 0.80 | DRD4 (0.70) | HTR7MAPTDRD4ALDH1A1 | |
| SCHEMBL5185365 | 0.80 | CA1 (0.58) | HTR7HTTNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |