Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | CPA3 | P15088 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745131 | 0.92 | FOLH1 (0.34) | CYP2C19CPA1CPB1CPA3CPB2 | |
| SCHEMBL8745128 | 0.88 | FOLH1 (0.45) | CYP2C19CPA3FOLH1PTGER1PTGER4 | |
| SCHEMBL7093743 | 0.78 | CPA1 (0.64) | CPA1CPB1CPA3CPB2FOLH1 | |
| SCHEMBL5674593 | 0.78 | CYP2C19 (0.64) | CYP2C19FOLH1ALDH1A1POLBHPGD | |
| SCHEMBL4885034 | 0.75 | HTT (0.56) | CYP2C19ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL8435170 | 0.74 | ALDH1A1 (0.58) | CYP2C19CPA1CPB1CPA3CPB2 | |
| SCHEMBL6389194 | 0.74 | ALDH1A1 (0.50) | CYP2C19ALDH1A1POLBHPGDCYP2C9 | |
| SCHEMBL11618413 | 0.71 | CPA1 (0.40) | CPA1CPB1CPA3CPB2FOLH1 | |
| SCHEMBL1026465 | 0.71 | ALDH1A1 (0.42) | CYP2C19ALDH1A1POLBHPGDCYP2C9 | |
| SCHEMBL6392514 | 0.70 | ALDH1A1 (0.46) | CYP2C19ALDH1A1POLBHPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0462670-B1 | Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0462644-B1 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-10-18 | — | — | EP | claimed |