Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 10/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745154 | 0.88 | CYP2C19 (0.39) | FOLH1CYP2C19CPA3PTGER1PTGER4 | |
| SCHEMBL5674593 | 0.83 | CYP2C19 (0.64) | FOLH1CYP2C19PTGER1PTGER4PTGER3 | |
| SCHEMBL8745131 | 0.81 | FOLH1 (0.34) | FOLH1CYP2C19CPA3 | |
| SCHEMBL8745187 | 0.80 | CPA3 (0.66) | FOLH1CPA3 | |
| SCHEMBL8745143 | 0.74 | CPA3 (0.40) | FOLH1CPA3 | |
| SCHEMBL8436879 | 0.74 | CYP2C19 (0.44) | FOLH1CYP2C19PTGER1PTGER4PTGER3 | |
| SCHEMBL4885034 | 0.74 | HTT (0.56) | CYP2C19 | |
| SCHEMBL8435236 | 0.73 | CYP2C19 (0.50) | CYP2C19 | |
| SCHEMBL8745112 | 0.73 | HPGD (0.51) | FOLH1CYP2C19 | |
| SCHEMBL8436342 | 0.73 | CYP2C19 (0.43) | FOLH1CYP2C19PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0462670-B1 | Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0462644-B1 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-10-18 | — | — | EP | claimed |