SCHEMBL7093743

SCHEMBL7093743

C=Cc1ccc(CC(CC(=O)O)C(=O)O)cc1

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CPA1 P15085 4/20 0.64
CPA3 P15088 2/20 0.64
CPB1 P15086 1/20 0.64
CPB2 Q96IY4 1/20 0.64
FOLH1 Q04609 1/20 0.49
MME P08473 6/20 0.48
CYP1A2 P05177 1/20 0.47
LTA4H P09960 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17537907 0.86 CPA1 (0.84) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL8745187 0.84 CPA3 (0.66) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL5146874 0.80 LDHA (0.52) CYP1A2
SCHEMBL11822629 0.80 CPA1 (0.39) CPA1CPA3CPB1CPB2MME
SCHEMBL24897644 0.80 ITGB3 (0.41) CPA1CPA3CPB1CPB2LTA4H
SCHEMBL15238580 0.80 SLC1A3 (0.67)
SCHEMBL15310772 0.80 SLC1A3 (0.67)
SCHEMBL11618413 0.79 CPA1 (0.40) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL3205288 0.79 CPA1 (0.72) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL1915564 0.78 CPA1 (1.00) CPA1CPA3CPB1CPB2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP claimed
EP-0462670-B1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same JOHNSON & JOHNSON CLIN DIAG (US) 1996-08-21 EP claimed
EP-0462644-B1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1995-10-18 EP claimed
US-6670410-B2 Containing vinyl polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-12-30 US disclosed