SCHEMBL8745191

SCHEMBL8745191

[CH2]CCC(=O)OCCN(C)c1cc[c]cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.35
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
GAA P10253 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
CDYL Q9Y232 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LTA4H P09960 2/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRM3 P20309 1/20 0.31
CHRNA4 P43681 1/20 0.31
PHLPP2 Q6ZVD8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6554111 0.80 RAD52 (0.42) ALDH1A1GAACHRM2CHRM4CHRM5
SCHEMBL6555905 0.78 SMN1; SMN2 (0.47) SMN1; SMN2CYP1A2GAALTA4HL3MBTL1
SCHEMBL11331220 0.74 KMT2A (0.47) ALDH1A1SMN1; SMN2GAALTA4HMTNR1A
SCHEMBL5145700 0.73 SMN1; SMN2 (0.41) ALDH1A1SMN1; SMN2CYP1A2TDP1CHRM1
SCHEMBL8895872 0.72 DNM1 (0.59) DNM1ALDH1A1SMN1; SMN2CYP1A2CYP3A4
SCHEMBL12088121 0.72 SMN1; SMN2 (0.50) DNM1ALDH1A1SMN1; SMN2CYP1A2CDYL
SCHEMBL3040413 0.71 BRAF (0.34) KDM4E
SCHEMBL9188800 0.71 DNM1 (0.44) DNM1ALDH1A1SMN1; SMN2CYP1A2CYP3A4
SCHEMBL6555103 0.70 LTA4H (0.34) LTA4HL3MBTL1
SCHEMBL8745129 0.70 ALDH1A1 (0.42) ALDH1A1GAATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP claimed
US-5210289-A Homo or coploymers for medical diagnosis EASTMAN KODAK COMPANY (US) 1993-05-11 US claimed
US-5155166-A Diagnostic kits for detecting antibodies or antigens; reacting active amine- or sulfhydryl-containing compound with quaternized carboxylic polymers EASTMAN KODAK COMPANY (US) 1992-10-13 US claimed
US-5149737-A Carboxy group extended from polymer surface allows easier attachment of biological substances EASTMAN KODAK COMPANY (US) 1992-09-22 US claimed
US-5147777-A Analysis, diagnosis EASTMAN KODAK COMPANY (US) 1992-09-15 US claimed
EP-0466220-A2 Carboxy containing monomers and polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-15 EP claimed
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP disclosed
EP-0462670-B1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same JOHNSON & JOHNSON CLIN DIAG (US) 1996-08-21 EP disclosed
EP-0468585-B1 Biologically active reagent, analytical element and methods for use of the reagent JOHNSON & JOHNSON CLIN DIAG (US) 1995-11-08 EP disclosed
EP-0462644-B1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1995-10-18 EP disclosed
US-5330891-A Method for detection of a nucleic acid using particulate reagent having polyoxyalkylene side chains EASTMAN KODAK COMPANY (US) 1994-07-19 US disclosed
US-5278267-A Water insoluble vinyl aromatic polymer EASTMAN KODAK COMPANY (US) 1994-01-11 US disclosed
US-5262297-A Medical diagnosis with active materials bound to polymers EASTMAN KODAK COMPANY (US) 1993-11-16 US disclosed
US-5155166-A Diagnostic kits for detecting antibodies or antigens; reacting active amine- or sulfhydryl-containing compound with quaternized carboxylic polymers EASTMAN KODAK COMPANY (US) 1992-10-13 US disclosed
US-5149737-A Carboxy group extended from polymer surface allows easier attachment of biological substances EASTMAN KODAK COMPANY (US) 1992-09-22 US disclosed
US-5147777-A Analysis, diagnosis EASTMAN KODAK COMPANY (US) 1992-09-15 US disclosed
EP-0468585-A2 Biologically active reagent, analytical element and methods for use of the reagent Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-29 EP disclosed
EP-0466220-A2 Carboxy containing monomers and polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-15 EP disclosed
EP-0462670-A1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP disclosed
EP-0462644-A1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP disclosed