Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745224 | 0.89 | NFE2L2 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8745250 | 0.84 | NFE2L2 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8745169 | 0.84 | NFE2L2 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8745288 | 0.83 | TRPA1 (0.32) | — | |
| SCHEMBL8745308 | 0.82 | AR (0.32) | — | |
| SCHEMBL8745245 | 0.82 | SLC6A4 (0.35) | — | |
| SCHEMBL8745240 | 0.81 | EPHX2 (0.35) | — | |
| SCHEMBL8745628 | 0.79 | NFE2L2 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8745643 | 0.79 | TRPA1 (0.34) | — | |
| SCHEMBL8745214 | 0.78 | TLR4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |