Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745224 | 0.96 | NFE2L2 (0.39) | NFE2L2TRPA1PABPC1RAB9AEIF4H | |
| SCHEMBL8745628 | 0.91 | NFE2L2 (0.41) | NFE2L2TRPA1PABPC1RAB9AEIF4H | |
| SCHEMBL8745260 | 0.88 | NFE2L2 (0.39) | NFE2L2TRPA1PABPC1RAB9AEIF4H | |
| SCHEMBL8745169 | 0.88 | NFE2L2 (0.39) | NFE2L2TRPA1PABPC1RAB9AEIF4H | |
| SCHEMBL8745643 | 0.85 | TRPA1 (0.34) | TRPA1TUBB1 | |
| SCHEMBL8745206 | 0.84 | KDM1A (0.36) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8745176 | 0.84 | NFE2L2 (0.36) | NFE2L2TRPA1PABPC1RAB9AEIF4H | |
| SCHEMBL8745185 | 0.84 | NFE2L2 (0.38) | NFE2L2TRPA1 | |
| SCHEMBL8745288 | 0.82 | TRPA1 (0.32) | TRPA1TUBB1 | |
| SCHEMBL8745308 | 0.81 | AR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |