Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745176 | 0.96 | NFE2L2 (0.36) | NFE2L2MAPTATMTRPA1TNNC1 | |
| SCHEMBL8745628 | 0.91 | NFE2L2 (0.41) | NFE2L2MAPTATMTRPA1PABPC1 | |
| SCHEMBL8745250 | 0.88 | NFE2L2 (0.41) | NFE2L2TRPA1PABPC1RAB9AEIF4H | |
| SCHEMBL8745169 | 0.87 | NFE2L2 (0.39) | NFE2L2TRPA1PABPC1RAB9AEIF4H | |
| SCHEMBL8745171 | 0.86 | PKM (0.32) | MAPTATMTRPA1CYP3A4CYP2C8 | |
| SCHEMBL8745156 | 0.85 | TNNC1 (0.38) | NFE2L2MAPTTRPA1TNNC1 | |
| SCHEMBL8745224 | 0.84 | NFE2L2 (0.39) | NFE2L2TRPA1PABPC1RAB9AEIF4H | |
| SCHEMBL8745188 | 0.83 | PKM (0.30) | TRPA1PKM | |
| SCHEMBL8747211 | 0.83 | MAPT (0.31) | MAPTATM | |
| SCHEMBL9139977 | 0.82 | EPHX2 (0.34) | MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |