Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745311 | 0.96 | TNNC1 (0.43) | TNNC1CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL8745203 | 0.91 | TNNC1 (0.45) | TNNC1CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL8745150 | 0.91 | TNNC1 (0.45) | TNNC1CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL8745257 | 0.91 | TNNC1 (0.35) | TNNC1CYP2C9CYP2C19ALOX5PTGS1 | |
| SCHEMBL8745334 | 0.88 | ALOX5 (0.35) | TNNC1CYP2C9CYP2C19ALOX5PTGS1 | |
| SCHEMBL8745261 | 0.87 | TNNC1 (0.36) | TNNC1MAPTLMNA | |
| SCHEMBL8745255 | 0.86 | TNNC1 (0.48) | TNNC1CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL8745162 | 0.86 | TNNC1 (0.48) | TNNC1CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL8745194 | 0.86 | TNNC1 (0.37) | TNNC1CYP2C9CYP2C19ALOX5PTGS1 | |
| SCHEMBL8745280 | 0.86 | TNNC1 (0.45) | TNNC1CYP2C9CYP3A4CYP2D6S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |