Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745194 | 0.96 | TNNC1 (0.37) | TNNC1ALOX5PTGS1PTGS2TUBB1 | |
| SCHEMBL8745334 | 0.91 | ALOX5 (0.35) | TNNC1ALOX5PTGS1PTGS2TUBB1 | |
| SCHEMBL8745282 | 0.91 | TNNC1 (0.41) | TNNC1ALOX5PTGS1PTGS2TUBB1 | |
| SCHEMBL8745253 | 0.90 | MAOA (0.40) | TNNC1TLR4CYP2C9MAOAMAOB | |
| SCHEMBL8745218 | 0.87 | MAOB (0.35) | TLR4MEN1LMNAMAPTKMT2A | |
| SCHEMBL8745292 | 0.87 | ALOX5 (0.37) | TNNC1ALOX5PTGS1PTGS2TUBB1 | |
| SCHEMBL8745280 | 0.87 | TNNC1 (0.45) | TNNC1PTGS1PTGS2LMNAKDM4E | |
| SCHEMBL8745311 | 0.86 | TNNC1 (0.43) | TNNC1ALOX5PTGS1PTGS2TUBB1 | |
| SCHEMBL8745626 | 0.86 | TRPA1 (0.35) | TLR4MAOAMAOB | |
| SCHEMBL8745290 | 0.85 | MAOB (0.43) | TNNC1MEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |