SCHEMBL8745319

SCHEMBL8745319

CC1=Nc2nc(C)nc(N)c2[N]1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2733366 0.83 DGAT1 (0.30) DGAT1
SCHEMBL8010167 0.64
SCHEMBL545836 0.64
SCHEMBL4330004 0.63 HSP90AB1 (0.33)
SCHEMBL2371337 0.61 LMNA (0.39)
SCHEMBL6424033 0.61 HSP90AB1 (0.36)
SCHEMBL16094459 0.59 ADORA1 (0.39)
SCHEMBL5049640 0.56 PI4KA (0.33) DGAT1
SCHEMBL1396931 0.56 LMNA (0.35)
SCHEMBL1830380 0.56 LMNA (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0754046-A1 USE OF PHOSPHONYLMETHOXYALKYL NUCLEOSIDES FOR THE TREATMENT OF RAISED INTRAOCULAR PRESSURE FREEMAN, William R. (US) 1997-01-22 EP claimed
WO-1995026734-A1 USE OF PHOSPHONYLMETHOXYALKYL NUCLEOSIDES FOR THE TREATMENT OF RAISED INTRAOCULAR PRESSURE FREEMAN WILLIAM R (US) 1995-10-12 WO claimed
EP-0754046-A1 USE OF PHOSPHONYLMETHOXYALKYL NUCLEOSIDES FOR THE TREATMENT OF RAISED INTRAOCULAR PRESSURE FREEMAN, William R. (US) 1997-01-22 EP disclosed
WO-1995026734-A1 USE OF PHOSPHONYLMETHOXYALKYL NUCLEOSIDES FOR THE TREATMENT OF RAISED INTRAOCULAR PRESSURE FREEMAN WILLIAM R (US) 1995-10-12 WO disclosed