SCHEMBL196585

SCHEMBL196585

Nc1ccccc1C(=O)NCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.55
KDM4E B2RXH2 9/20 0.55
HPGD P15428 7/20 0.55
KEAP1 Q14145 1/20 0.54
MAPT P10636 2/20 0.53
HIF1A Q16665 1/20 0.53
SLC22A6 Q4U2R8 1/20 0.53
SLC22A8 Q8TCC7 1/20 0.53
NSD2 O96028 2/20 0.51
HSD17B10 Q99714 3/20 0.51
RCE1 Q9Y256 1/20 0.51
TP53 P04637 1/20 0.49
MAPK1 P28482 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
GAA P10253 1/20 0.48
USP2 O75604 1/20 0.48
EGLN1 Q9GZT9 1/20 0.48
HDAC1 Q13547 1/20 0.48
CFTR P13569 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28160698 0.98 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDKEAP1MAPT
SCHEMBL4062229 0.98 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDKEAP1MAPT
SCHEMBL31448014 0.86 KEAP1 (0.62) KDM4EKEAP1MAPTHIF1ASLC22A6
SCHEMBL12311981 0.86 MMP2 (0.59) ALDH1A1KDM4EHPGDKEAP1MAPT
SCHEMBL15630971 0.83 KEAP1 (0.49) ALDH1A1KDM4EHPGDKEAP1MAPT
SCHEMBL8745364 0.82 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDMAPTNSD2
SCHEMBL31267447 0.82 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDNSD2HSD17B10
SCHEMBL233364 0.82 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDNSD2HSD17B10
SCHEMBL4955428 0.82 ALDH1A1 (0.59) ALDH1A1KDM4EHPGDNSD2HSD17B10
Aminohippuric Acid SCHEMBL8351356 0.81 MAPT (0.71) ALDH1A1KDM4EKEAP1MAPTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 840 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-119350093-A Preparation method of slow-release urea and application of slow-release urea in saline-alkali soil remediation 西北师范大学 2025-01-24 CN claimed
US-20240390364-A1 Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions REID CHRISTOPHER BRIAN (US) 2024-11-28 US claimed
US-20230158041-A1 METHODS AND COMPOSITIONS FOR TREATING AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2023-05-25 US claimed
US-20230074763-A1 IDENTIFICATION OF HOST-TARGETING MODULATORS OF BACTERIAL UPTAKE AND ASSAY FOR QUANTIFYING INTRACELLULAR BACTERIA UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2023-03-09 US claimed
EP-3965751-B1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE ITM ISOTOPE TECH MUNICH SE (DE) 2022-12-28 EP claimed
WO-2022096103-A1 COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER ITM Isotopen Technologien München AG (DE) 2022-05-12 WO claimed
CN-114126654-A Para-aminohippuric acid (PAH) as a kidney protective substance 同位素技术慕尼黑有限公司 2022-03-01 CN claimed
US-20210331145-A1 HYDROGENATION PROCESS COMPRISING A CATALYST PREPARED BY ADDITION OF AN ORGANIC COMPOUND IN THE GAS PHASE IFP Energies Nouvelles (FR) 2021-10-28 US claimed
EP-2459227-B1 Prodrugs containing an aromatic amine connected by an amide bond to a carrier ASCENDIS PHARMA AS (DK) 2021-03-17 EP claimed
US-20080306025-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2008-12-11 US claimed
EP-1979366-A2 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE Yu, Ruey J. (US) 2008-10-15 EP claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007087013-A2 FUNCTIONAL IMMUNOASSAY BIOPAL, INC. (US) 2007-08-02 WO claimed
WO-2007082206-A2 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J (US) 2007-07-19 WO claimed
US-20070161543-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2007-07-12 US claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-7176185-B2 Short peptide carrier system for cellular delivery of agent TSRL, INC. (US) 2007-02-13 US claimed
US-20050137141-A1 Prodrug composition HILFINGER JOHN (US) 2005-06-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158041-A1 METHODS AND COMPOSITIONS FOR TREATING AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE ABCC3, HTR3A, PKD1 ALDH1A1 2687/4885KDM4E 4358/4885HPGD 2138/4885
US-20050137141-A1 Prodrug composition CYP3A5, SLC35B2, SLC1A5 ALDH1A1 1392/4885KDM4E 564/4885HPGD 1799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.