Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745367 | 0.81 | MAPT (0.45) | MAPTALDH1A1POLBMEN1USP2 | |
| SCHEMBL23797087 | 0.75 | ALDH1A1 (0.48) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL20729515 | 0.75 | ALDH1A1 (0.48) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL2932044 | 0.74 | MAPT (0.47) | MAPTALDH1A1POLBMEN1USP2 | |
| SCHEMBL8447329 | 0.74 | CHRNB2 (0.41) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL14110267 | 0.73 | MAPT (0.62) | MAPTALDH1A1POLBMEN1USP2 | |
| SCHEMBL14110269 | 0.73 | MAPT (0.62) | MAPTALDH1A1POLBMEN1USP2 | |
| SCHEMBL3089802 | 0.73 | MAPT (0.41) | MAPTALDH1A1POLBMEN1USP2 | |
| SCHEMBL3024504 | 0.72 | ALDH1A1 (0.46) | MAPTALDH1A1POLBMEN1USP2 | |
| SCHEMBL30708946 | 0.72 | ALDH1A1 (0.46) | MAPTALDH1A1POLBMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276143-A | Dideoxyfructonucleosides and deoxyfructonucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-04 | — | — | US | disclosed |