Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3189794 | 0.87 | ALDH1A1 (0.36) | MAPTALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL3078227 | 0.87 | ALDH1A1 (0.36) | MAPTALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL8745367 | 0.74 | MAPT (0.45) | MAPTALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL8745366 | 0.73 | MAPT (0.50) | MAPTALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL2932044 | 0.69 | MAPT (0.47) | MAPTALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL14110269 | 0.68 | MAPT (0.62) | MAPTALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL14110267 | 0.68 | MAPT (0.62) | MAPTALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL30708946 | 0.67 | ALDH1A1 (0.46) | MAPTALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL3024504 | 0.67 | ALDH1A1 (0.46) | MAPTALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL28604390 | 0.67 | MAPT (0.57) | MAPTALDH1A1LGALS9LGALS1LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278282-B2 | Nucleoside analogs for treatment of viral infections | NOVARTIS AG (CH) | 2012-10-02 | — | — | US | disclosed |
| US-20100227833-A1 | NOVEL NUCLEOSIDE ANALOGS FOR TREATMENT OF VIRAL INFECTIONS | NOVARTIS PHARMA AG (CH) | 2010-09-09 | — | — | US | disclosed |
| US-20100144655-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227833-A1 | NOVEL NUCLEOSIDE ANALOGS FOR TREATMENT OF VIRAL INFECTIONS | MAVS, HAVCR2, SAMHD1 | MAPT 3531/4885ALDH1A1 2629/4885LGALS9 852/4885 |
| US-20100144655-A1 | ORGANIC COMPOUNDS | OAT, MAVS, HAVCR2 | MAPT 1221/4885ALDH1A1 137/4885LGALS9 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.