Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20729515 | 0.77 | ALDH1A1 (0.48) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL23797087 | 0.77 | ALDH1A1 (0.48) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL8745381 | 0.77 | NPC1 (0.40) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL8447584 | 0.76 | CES2 (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL8448905 | 0.76 | CES2 (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL8745371 | 0.76 | NPC1 (0.42) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL28498515 | 0.76 | MAPK1 (0.50) | NPC1ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL8447125 | 0.76 | CES2 (0.48) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL16148176 | 0.75 | TSHR (0.38) | CHRNB2CHRNA5CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL8745366 | 0.74 | MAPT (0.50) | CHRNB2CHRNA5CHRNA7CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502690-B1 | Cyclopropane derivative | AJINOMOTO KK (JP) | 1999-12-01 | — | — | EP | disclosed |
| US-5449840-A | Viricides | AJINOMOTO CO., INC. (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5342840-A | Viricides | AJINOMOTO CO., INC. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0502690-A2 | Cyclopropane derivative | Ajinomoto Co., Inc. (JP) | 1992-09-09 | — | — | EP | disclosed |