Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745308 | 0.93 | AR (0.32) | ARTRPV4CYP11B1CYP11B2DRD2 | |
| SCHEMBL8747211 | 0.92 | MAPT (0.31) | ARTRPV4CYP11B1CYP11B2DRD2 | |
| SCHEMBL8745169 | 0.86 | NFE2L2 (0.39) | — | |
| SCHEMBL8745628 | 0.81 | NFE2L2 (0.41) | — | |
| SCHEMBL8745226 | 0.81 | MAOB (0.39) | DRD2DRD3 | |
| SCHEMBL8745214 | 0.80 | TLR4 (0.32) | — | |
| SCHEMBL8745626 | 0.79 | TRPA1 (0.35) | DRD2DRD3 | |
| SCHEMBL8745389 | 0.79 | EPHX2 (0.35) | — | |
| SCHEMBL8745224 | 0.78 | NFE2L2 (0.39) | — | |
| SCHEMBL8745176 | 0.78 | NFE2L2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |