⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29284737 | 1.00 | — | — | |
| SCHEMBL10479238 | 0.86 | KMT2A (0.46) | — | |
| SCHEMBL30625753 | 0.82 | KMT2A (0.42) | — | |
| SCHEMBL202780 | 0.77 | ALDH1A1 (0.48) | — | |
| SCHEMBL202781 | 0.77 | ALDH1A1 (0.48) | — | |
| SCHEMBL475421 | 0.77 | LMNA (0.48) | — | |
| SCHEMBL317779 | 0.77 | LMNA (0.48) | — | |
| SCHEMBL78947 | 0.77 | LMNA (0.48) | — | |
| SCHEMBL26691621 | 0.77 | KMT2A (0.41) | — | |
| SCHEMBL3072002 | 0.76 | KMT2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509821-B1 | Substituted acetoxyazetidinone derivatives and process for preparing 4-acyloxyazetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 1995-12-27 | — | — | EP | claimed |
| EP-0509821-A1 | Substituted acetoxyazetidinone derivatives and process for preparing 4-acyloxyazetidinone derivatives | Takasago International Corporation (JP) | 1992-10-21 | — | — | EP | claimed |
| CN-119486739-A | α4β1/7Integrin ligand conjugated compounds and uses thereof | 阿达尔克斯制药有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-118221664-A | POLQ inhibitor | 水木未来(北京)科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-117756793-A | 1,2, 4-heterodiazole derivatives and use thereof | 四川大学 | 2024-03-26 | — | — | CN | disclosed |
| US-5629420-A | Substituted acetoxyazetidinone derivatives and process for preparing 4-acyloxyazetidinone derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-05-13 | — | — | US | disclosed |
| US-5606052-A | Substituted acetoxyazetidinone derivatives and process for preparing 4-acyloxyazetidinone derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0488611-B1 | Process for producing 4-acetoxyazetidinones | TAKASAGO PERFUMERY CO LTD (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0509821-B1 | Substituted acetoxyazetidinone derivatives and process for preparing 4-acyloxyazetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 1995-12-27 | — | — | EP | disclosed |
| US-5440030-A | Acidification of azetidinone or derivatives thereof | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5288862-A | Reacting azetidinone or derivative with carboxylic acid in presence of ruthenium compound, aldehyde, oxygen | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-02-22 | — | — | US | disclosed |
| US-5191076-A | Penicillin intermediates | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0509821-A1 | Substituted acetoxyazetidinone derivatives and process for preparing 4-acyloxyazetidinone derivatives | Takasago International Corporation (JP) | 1992-10-21 | — | — | EP | disclosed |
| EP-0488611-A1 | Process for producing 4-acetoxyazetidinones | Takasago International Corporation (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0090340-A1 | Process for preparation of optically active 4-(2-Hydroxyethyl)-2-azetidinone | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-05 | — | — | EP | disclosed |